074188美國(guó)戴安Dionex Acclaim Trinity P1 Series 液相色譜柱
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產(chǎn)品名稱(chēng): 074188美國(guó)戴安Dionex Acclaim Trinity P1 Series 液相色譜柱
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簡(jiǎn)單介紹
【簡(jiǎn)單介紹】戴安公司生產(chǎn)的儀器主要有離子色譜儀、高效液相色譜儀、快速溶劑萃取儀和氨基酸直接分析儀。其中離子色譜儀憑借著雄厚的技術(shù)優(yōu)勢(shì)和方法已廣泛地應(yīng)用于各個(gè)領(lǐng)域，其市場(chǎng)占有率達(dá)80%。全球與離子色譜相關(guān)的文章有90%均出自戴安公司生產(chǎn)的離子色譜儀。
戴安公司的快速溶劑萃取儀15分鐘之內(nèi)僅用15毫升溶劑既可完成對(duì)10g樣品的萃取，該技術(shù)已在環(huán)境、**、食品和聚合
074188美國(guó)戴安Dionex Acclaim Trinity P1 Series 液相色譜柱
的詳細(xì)介紹
Acclaim Trinity P1 Series
Acclaim Trinity P1 is a unique, high-efficiency, silica-based column designed for pharmaceutical applications such as simultaneous separation of pharmaceutical drug substances and their counterions. This new column, based on nanopolymer silica hybrid (NSH) technology, provides multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange. As a result, its selectivity can be easily optimized by adjusting mobile phase buffer concentration, pH, and solvent content concurrently or independently. The NSH technology ensures distinctive spatial separation of the anion-exchange and cation-exchange regions, which results in maximum flexibility in method development. The easy-to-optimize selectivity can be used to accelerate chromatographic separations and increase productivity.
NSH Chromatographic Features
- Multiple retention mechanisms including reversed-phase, anion-exchange, and cation-exchange
- Adjustable selectivity by mobile phase ionic strength, electrolyte type, pH, and organic solvent
- Ideal selectivity for simultaneous separation of basic, neutral, and acidic analytes
- Separation of hydrophilic ionic and ionizable analytes without ion-pairing reagents
Acclaim Trinity P1 Applications
- Active pharmaceutical ingredients (API) and counterions (cations or anions)
- Screening of pharmaceutical counterions. Both UV and evaporative light scattering (ELS) detectors, in series, are required for simultaneous determination of both drug substances and counterions.
- Mixture of acidic and basic drug substances and respective counterions
- Drug substances of acidic, basic, and neutral mixtures
- High throughput analysis following optimization of the selectivity and resolution. The flow rate can then be increased, and the analysis time shortened.
技術(shù)參數(shù)：
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| Acclaim Trinity P1 Column – Superior Performance for Pharmaceutical Applications Specifications |
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| Column chemistry | SCX, WAX and RP Mixed-Mode |
| Operating pressure limit (recommended) | 4500 psi (4000 psi) |
| Operating pH range (recommended) | 2.5 – 7.0 (3.0 to 6.2) |
| Operating flow rate range (recommended) | 0.3 – 1.5(0.4 – 0.8) mL/min for 3.0-mm i.d. formats
0.15 – 0.80 (0.2 to 0.4) mL/min for 2.1-mm i.d. formats |
訂購(gòu)信息：
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| Analytical Columns |
|---|
| Acclaim Trinity P1, 3μm, 3.0 x 150mm | 075563 |
| Acclaim Trinity P1, 3μm Analytical, (3.0 x 100mm) | 071387 |
| Acclaim Trinity P1, 3μm Analytical, (3.0 x 50mm) | 071388 |
| Acclaim Trinity P1, 3μm, 2.1 x 150mm | 075564 |
| Acclaim Trinity P1, 3μm Analytical, (2.1 x 100mm) | 071389 |
| Acclaim Trinity P1, 3μm, 2.1 x 50mm | 075565 |
| Guard Columns |
|---|
| Acclaim Trinity P1, 3μm Guard Cartridges, (3.0 x 10mm), 2ea (Use Holder V-2) | 071390 |
| Acclaim Trinity P1, 3μm Guard Cartridges, (2.1 x 10mm), 2ea (Use Holder V-2) | 071391 |
| Acclaim SST Guard Cartridge Holder V-2 | 069580 |
| Acclaim Guard Kit (Holder and coupler) V-2 | 069707 |
| Guard to Analytical Column Coupler V-2 | 074188 |
